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How did myocardial infarction and cerebral infarction happen?

guoyifangheart @ 2020/06/29

There are many reasons for myocardial infarction and cerebral infarction, but the most common reason is the formation of atherosclerosis.
Simply speaking, atherosclerosis is the formation of atherosclerotic plaques. Plaque is getting bigger and bigger, which makes the arteries of the heart and brain narrow, resulting in heart and brain ischemia and anoxia. If the plaque suddenly ruptures, the blood platelets will quickly aggregate and form a thrombus, which will completely block the blood vessels and interrupt the blood flow of the arteries. The myocardial tissue or brain tissue in the corresponding area will be necrosis due to ischemia and hypoxia, which leads to myocardial infarction or cerebral infarction. Thus, the most basic pathological basis of myocardial infarction or cerebral infarction is the formation of atherosclerotic plaques.
Why do atherosclerotic plaques occur? Simply speaking, atherosclerotic plaques are the accumulation of cholesterol in the blood vessels and the formation of plaques. Everyone has cholesterol in their blood. Why do people form plaques and others do not? Whether plaque can be formed mainly depends on two factors: first, the higher the cholesterol level in the blood, the higher the cholesterol level, the more raw materials that form the plaque, the more vulnerable plaques are; the two is the integrity of the arterial endothelium. Normally, our vascular endothelium is very smooth and tight, and cholesterol is hard to enter. But a variety of factors can make the endothelium become incomplete, and cholesterol will take the opportunity to enter the plaque, leading to plaque formation. The common factors that can damage vascular endothelium include hypertension, diabetes, smoking, and advanced age.
Since the formation of atherosclerotic plaques is related to the above two factors, the prevention of plaque should be started from these two aspects. First of all, avoid high cholesterol levels in the blood. Controlling diet, improving diet structure, increasing exercise, controlling weight and not drinking are effective measures to avoid high cholesterol. If cholesterol is significantly elevated, it is necessary to receive medication under the guidance of a doctor (mainly by statin), lowering the level of cholesterol in the blood. Secondly, it is necessary to avoid factors that damage the vascular endothelium, such as prevention of hypertension and diabetes. If you already have hypertension and diabetes, you should adhere to long-term treatment under the guidance of doctors, which can significantly reduce the risk of vascular endothelial damage, thereby reducing the possibility of plaque formation.
Finally, it needs to be emphasized that all kinds of chronic diseases such as hypertension and diabetes need lifelong medication. There is no cure yet at home and abroad. Some rivers and lakes doctors and street swindlers often sell fake medicines. They claim to be able to cure hypertension, diabetes, coronary heart disease, cerebral infarction and so on. They are all deceptive, and they are money and lives. A few days ago, a friend of mine stopped listening to these false propaganda, stopped using antihypertensive drugs, took the so-called "international newest product" which could cure hypertension, and finally died of cerebral hemorrhage due to a sharp rise in blood pressure. I have also encountered patients who have been treated with the so-called "pure Chinese medicine" to treat diabetes. These lessons of blood should be taken as a warning.

(Hebei People's Hospital, Guo Yifang)